Allow F-Secure Anti-Virus to disinfect the relevant files.
For more general information on disinfection, please see Removal Instructions.
Eliminating a Local Network Outbreak
If the infection is in a local network, please follow the instructions on this webpage:
To manually disinfect an infected system, first apply the Microsoft patch MS04-011, then use Task Manager to kill the "lsasss.exe" process, then delete the file 'lsasss.exe' from your Windows directory and reboot.
For step-by-step instructions, see Microsoft's site: http://www.microsoft.com/security/incident/sasser.asp#steps
It has been modified by changing the main virus file name to LSASSS.EXE. Note that this has nothing to do with Windows' LSASS.EXE. Also the port numbers used for the shell and FTP server have been changed.
Also, Sasser.E tries to remove the Bagle worm, unlike earlier Sassers but just like many Netsky variants.
Two hours after infection Sasser.E displays the following message:
For more details on Sasser, see description of Sasser.D.