The June security update has something for nearly everyone. Microsoft released twelve updates addressing various issues yesterday. There are several for different flavors of Windows and IE, and others for Word (MS06-027), PowerPoint (MS06-028), and Media Player 10 (MS06-024).
The patch for Word fixes an issue that was blogged about in May. The PowerPoint includes versions for Windows and Mac - though the vulnerability is not likely to exploit either OS. Additional analysis is available here.
Edited to add: Here's some more information on the patches available and what they fix. Several of them have exploits. Update your systems soon.